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	Provedor de dados BJID (1) Genet. Mol. Biol. (1) Autor Boldt,Angelica B.W. (2) Culpi,Lodércio (1) Kun,Jürgen F.J. (1) Leitão,Cleverson (1) Messias-Reason,Iara J.T. (1) Petzl-Erler,Maria Luiza (1) Souza,Ilíada R. (1) Tsuneto,Luiza T. (1) Ueda,Denis (1) de Moraes Braga,Anna Carolina (1) Mais... Palavra-chave Amerindian (1) Brazilian (1) CCR5 (1) HBV (1) HIV (1) Hepatitis B (1) Leprosarium (1) Leprosy (1) Mycobacterium leprae (1) Polymorphism (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2014 (1) 2009 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Analysis of the CCR5 gene coding region diversity in five South American populations reveals two new non-synonymous alleles in Amerindians and high CCR5*D32 frequency in Euro-Brazilians Genet. Mol. Biol. Boldt,Angelica B.W.; Culpi,Lodércio; Tsuneto,Luiza T.; Souza,Ilíada R.; Kun,Jürgen F.J.; Petzl-Erler,Maria Luiza. The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The effect of the CCR5*D32 allele in susceptibility to HIV infection and AIDS disease is well known. Other alleles than CCR5*D32 have not been analysed before, neither in Amerindians nor in the majority of the populations all over the world. We investigated the distribution of the CCR5 coding region alleles in South Brazil and noticed a high CCR5*D32 frequency in the Euro-Brazilian population of the Paraná State (9.3%), which is the highest thus far reported for Latin America. The D32 frequency is even higher among the Euro-Brazilian Mennonites (14.2%). This allele is uncommon in Afro-Brazilians (2.0%), rare in the Guarani Amerindians (0.4%) and absent in the Kaingang... Tipo: Info:eu-repo/semantics/article Palavras-chave: CCR5; Brazilian; Amerindian; HIV; Polymorphism. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000100002 Leprosy and hepatitis B coinfection in southern Brazil BJID Leitão,Cleverson; Ueda,Denis; de Moraes Braga,Anna Carolina; Boldt,Angelica B.W.; Messias-Reason,Iara J.T.. To investigate the association of leprosy with hepatitis B virus (HBV) infection, as yet unknown for South Brazil, we assessed hepatitis B virus coinfection in 199 South Brazilian leprosy patients (119 lepromatous, 15 tuberculoid, 30 borderline, 12 undetermined and 23 unspecified) and in 681 matched blood donors by screening for the hepatitis B virus markers HBSAg and anti-HBc, using ELISA. Positive samples were retested and anti-HBc+ only samples were tested for the hepatitis B surface antibody (anti-HBs). There was a strong association between leprosy and hepatitis B virus infection (OR = 9.8, 95% CI = 6.4–14.7; p = 0.004·E−30), as well as an association between HBV infection and lepromatous leprosy, compared to other forms (OR = 2.4, 95% CI = 1.2–4.8; p... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leprosy; Hepatitis B; Leprosarium; HBV; Mycobacterium leprae. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100008 Registros recuperados: 2 Primeira ... 1 ... Última

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